The O-Shot: Miracle Injection? (2024)

Call it the shot heard round the world—only this time the revolution is on behalf of modern women. The O-Shot, a new, noninvasive treatment that aims to alleviate female sexual dysfunction by extracting PRP, or platelet-rich plasma, from a woman's own blood and injecting it directly into the vagin*l area.

As Charles Runels, an Alabama cosmetic doctor (who's better known as the creator of the Vampire Facial, made famous when Kim Kardashian had the procedure done on TV), explains, the O-Shot uses PRP to stimulate the growth of new cells in a woman's vagin*l walls and cl*tor*s. The platelets, which the body utilizes to naturally generate tissue, increase not only the number of cells but also, Runels claims, sensitivity to stimulation.

Runels says that he was inspired by the array of treatments available for men dealing with sexual problems—with everything from Viagra to penile implants as a remedy—and the glaring void when it came to female sexual dysfunction, even though more than 40 percent of American women are estimated to suffer from it. There was nothing similar for women, recalls Samuel Wood, a San Diego reproductive endocrinologist who began a clinical trial on the procedure in 2011. Now he and Runels are hopeful that the in-office treatment, which takes about 20 minutes and can be done only by a certified doctor or nurse-practitioner, will be the answer both for those women and for others looking to boost a less than satisfying sex life.

Take Nadia*, 39, a mother of three who found sex with her fiancé lacking. In her younger days, she says, "I was turned on whenever the guy was," but by her late 30s, getting to that same level of arousal "required so much foreplay, I was ready to give up." Though she tried over-the-counter lubricants, she complained that they didn't last. When she heard about the O-Shot, she decided to give it a try. She says she now has an org*sm every time she has sex, "stronger ones than I used to have when I was younger."

Similarly, Gail*, 53, has been married for 20 years and had resigned herself to lackluster, once-a-month lovemaking. "I wasn't really aroused no matter what we did," she says. So when her nurse-practitioner suggested the shot, she was more than willing. The result? She noticed an immediate effect, and she returned home from work that day ready to go. Whereas before, she'd fake org*sms and felt "inadequate," she now looks forward to sex.

So how does the O-Shot work? First, the patient's blood is drawn (about half a tablespoon) and placed in a centrifuge to separate out the PRP. To determine where an injection will have maximum results, Wood does "vagin*l mapping," asking the patient where she's most sensitive, and then an anesthetic cream is applied to the area. "You have to understand each woman's sexuality and her anatomy to know where to put it," he explains. The procedure, which costs $1,200 to $1,500 and isn't covered by insurance, has the added benefit of creating what he refers to as an immediate volumizing effect, which lasts up to a week. The real payoff, though, comes over the next few months as the PRP "stimulates the stem cells, collagen, and blood vessels," says Runels, who calls it "fertilizer to grow the tissue." (The overall effect should last at least 18 months.)

As for safety, Runels says that no serious side effects have been reported. The treatment itself doesn't require FDA oversight, although an FDA-cleared kit is required to prepare the plasma. And it has plenty of skeptics. Laura Berman, author of Loving Sex: The Book of Joy and Passion, is concerned about the lack of scientific studies thus far. (Results of both Runels's and Wood's clinical trials will be published this year.) "There's no mechanism of action that I can see that would really facilitate arousal and org*sm," Berman says. "It feels like they're taking advantage of a valid longing that millions of women have and stating a claim that hasn't been supported in any substantial way other than through anecdotal reports."

Perhaps Dena Harris, a New York gynecologist who has treated women suffering from vulvar pain with PRP and is interested in seeing study results, sums it up best: "I don't know if it works, but I really hope it does." *Names have been changed

The O-Shot: Miracle Injection? (2)

Rachel Kramer Bussel

Rachel Kramer Bussel ( writes about sex, dating, books and pop culture. She's the editor of over 60 anthologies including The Big Book of org*sms, Come Again: Sex Toy Erotica and the Best Women's Erotica of the Year series, and teaches erotica writing classes in person and online. Follow her on Twitter @raquelita.

The O-Shot: Miracle Injection? (2024)


Does the O Shot work for everyone? ›

The results can vary depending on the patient's starting point. For example, factors such as age, medical conditions, and hormonal problems can determine the results.

What is the success rate of the O Shot? ›

Sexual function improvements from the O-Shot® have been estimated in 75-95% of women! Within days after the treatment, most women report a noticeable improvement in their sexual arousal and org*sm intensity. The full effects of the treatment will most likely manifest after 3 months.

How many O shots do you need? ›

“O-Shot requires a series of treatments first, typically monthly for three treatments,” Dr. Emer says. After the initial three sessions, the patient can come in every three to six months to “maintain results and prevent the symptoms of aging in this area,” he adds.

Does o Shot make you tighter? ›

This means that when a patient gets the Femilift and adds the O-Shot, she gets the benefits of vagin*l tightening, more stimulation, and better org*sms than if she did only one or the other.

How long does it take to get the results of an O shot? ›

Most women notice a heightened vagin*l sensation within the first three to seven days. After three weeks, new tissue will begin to develop and continue for up to nine weeks. At the three-month mark, the O-shot reaches its peak development. The effects will last for roughly a year.

What are the negative effects of the O shot? ›

What Are the Potential Side Effects of the O-Shot®? Since PRP is extracted from your own blood, there are few and only minor potential side effects. These include minor bleeding or bruising, swelling, and very rarely infection.

How much does the O Shot cost with insurance? ›

You can expect to pay between $1,400-$1,800 for a single O Shot®. Since the O Shot® is considered an elective procedure, health insurance does not cover the cost.

Does o Shot change appearance? ›

Other potential benefits of the O-Shot include increased vagin*l lubrication, improved vagin*l tone and elasticity, and relief from vagin*l dryness and discomfort. It can also help improve the appearance of the vagin*l area, as the PRP can stimulate the growth of new tissue and collagen growth.

Is an O Shot painful? ›

Patients' pain tolerances vary, however The O-Shot creates little, if any, pain. The areas are numbed with a topical cream, however some women may feel a pinching or stinging sensation while others don't feel anything.

Does the O shot increase lubrication? ›

After receiving the shot treatment, many patients report stronger org*sms, increased natural lubrication, enhanced arousal, and reduced urinary incontinence.

Is O Shot FDA approved? ›

Is O-shot® Approved By the FDA? The Food and Drug Administration (FDA) does not govern blood biologics. However, the device that is approved by the FDA to prepare the PRP that's used in the O-Shot® is approved by the FDA.

What to do before getting the O shot? ›

AVOID the Systemic use of corticosteroids for 1 week before the procedure. AVOID Alcohol and Cigarettes for 5 days before the procedure. HYDRATE very well the day before and the day of the procedure for ease of blood draw. SHAVE the treatment area within 24 hours of procedure.

Do O shots really work? ›

AL Aesthetics' O-Shot treatment increases blood flow to the cl*tor*s, G-spot, and surrounding tissues, resulting in improved sensitivity and heightened sensations during sexual stimulation. The procedure offers an entire range of benefits including: Increase in libido. Enhanced arousal.

What is O-Shot vs G Shot? ›

The G-Shot is injected into the G-spot inside the vagin*, while the O-Shot goes into the upper vagin* and near the cl*tor*s. These procedures are performed by a licensed healthcare professional. Even though both are good options, they're not the same. Knowing the differences can help you choose the right one for you.

What is the difference between the O-Shot and the P Shot? ›

What are the P-Shot and O-Shot? The P-Shot for men and the O-shot for women are two types of platelet-rich plasma treatments that optimize sexual health and enjoyment.

Who is a candidate for the O Shot? ›

Women of many ages can be candidates for the O-Shot. A large number of candidates are menopausal women who are concerned about a decreased libido, vagin*l dryness, and/or difficulty stimulating the G-spot and/or cl*tor*s for a satisfying sexual experience.

What to do before getting the O Shot? ›

AVOID the Systemic use of corticosteroids for 1 week before the procedure. AVOID Alcohol and Cigarettes for 5 days before the procedure. HYDRATE very well the day before and the day of the procedure for ease of blood draw. SHAVE the treatment area within 24 hours of procedure.

Can you get the O Shot while on your period? ›

Because a woman's period does not originate from or affect the outer layers of the vagin*, women who are on their period are able to receive the O-Shot.

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